Welcome to Biomaterials, Inflammation, and Tissue Engineering (BITE) Lab

We are a passionate research group at the F. Joseph Halcomb III, M.D. Department of Biomedical Engineering. We are interested in understanding the mechanobiology of the immune cells and immunomodulatory cells in neotissue formation and tissue repair and applying this knowledge to the development of regenerative therapies. To this end, we study the role of macrophages and mesenchymal stromal cells in bone fracture healing and pathological conditions to elucidate their regenerative potential. My lab also develops microengineered material systems and immunomodulatory biomaterials for promoting tissue regeneration and wound healing. Our research span both basic and translational research areas. 

Our team collaborates with leading experts at the colleges of Medicine, Arts and Sciences, Pharmacy, Engineering, and Dentistry in understanding various aspects of inflammation in diseases and in developing suitable immunomodulatory therapies.

  We are looking for energetic and passionate graduate and undergraduate students with chemical engineering, material science, mechanical engineering or biology background to join the team. Please directly email Dr. Ramkumar Annamalai for more information (more info)

We are grateful for funding from the College of Engineering and the Biomedical Engineering at UK, Centre for Clinical and Translational Sciences at UK, Centre for Pharmaceutical Research and Innovation at UK, and National Institute of Health (NIGMS). 


Nov 11, 2022

Congrats, Alex, on succesfully defending your Master's research. Good luck with yout future endeavours.

Oct 30, 2022

Congrats, Kate, on giving excellent research presentations and receving the 2nd best poster award at the 2022 Biomaterials Day held at Vanderbilt University! #Proud PI

Oct 20, 2022

Congrats, BITErs, on giving excellent research presentations at the 2022 BMES Annual meeting in San Antonio. You are the best! #Proud PI

Sep 23, 2022

Congrats, Matt, Jeremy, and Harshini on your recent paper developing injectable nanoporous microgels generate vascularized constructs Link.

Aug 20, 2022

Congrats, Matt, on your recent paper developing licensing microgels to modulate inflammation Link.

Feb 07, 2022

Congrats Team for getting this R21 grant award for our nanomedicine research. See the press release here.

Feb 07, 2022

Congrats Team for getting this Orthopedic Trauma Association grant. See the press release here.

Dec 10, 2021

Congrats Harshini for getting Professional Development Grant Award from the Center for Graduate & Professional Diversity Initiatives (CGPDI)

Oct 10, 2021

Great presentations by our amazing students at BMES 2021 (Orlando).

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